3-(2,3-Dioxoindolin-1-yl)propanenitrile

被引：3
|
作者：
Qachchachi, Fatima-Zahrae [1 ]
Rodi, Youssef Kandri [1 ]
Essassi, El Mokhtar [2 ]
Bodensteiner, Michael [3 ]
El Ammari, Lahcen [4 ]
机构：
[1] Univ Sidi Mohamed Ben Abdallah, Fac Sci & Techn, Lab Chim Organ Appl, Route Immouzzer,BP 2202, Fes, Morocco
[2] Univ Mohammed Agdal, Lab Chim Organ Heterocycl, URAC 21, Pole Competences Pharmacochimie, Rabat, Morocco
[3] Univ Regensburg, X Ray Struct Anal Unit, D-93053 Regensburg, Germany
[4] Univ Mohammed Agdal, Fac Sci, Lab Chim Solide Appl, Rabat, Morocco
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2014年 / 70卷
关键词：
Data-to-parameter ratio = 13.1; Mean σ(C-C) = 0.002 Å; R factor = 0.033; Single-crystal X-ray study; T = 123 K; wR factor = 0.086;
D O I：
10.1107/S1600536814003985
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The asymmetric unit of the title compound, C11H8N2O2, contains two independent molecules (A and B). Each molecule is build up from fused five-and six-membered rings with the former linked to a cyanoethyl group. The indoline ring and two carbonyl O atoms of each molecule are nearly coplanar, with the largest deviations from the mean planes being 0.0198 (9) (molecule A) and 0.0902 (9) angstrom (molecule B), each by a carbonyl O atom. The fused ring system is nearly perpendicular to the mean plane passing through the cyanoethyl chains, as indicated by the dihedral angles between them of 69.72 (9) (molecule A) and 69.15 (9)degrees (molecule B). In the crystal, molecules are linked by C-H center dot center dot center dot O and pi-pi [intercentroid distance between inversion-related indoline (A) rings = 3.6804 (7) angstrom] interactions into a double layer that stacks along the a-axis direction.
引用
收藏
页码：O361 / +
页数：9
相关论文
共 50 条
  • [41] Stereoisomers of 3-(2,3-dihydrobenzofuran-2-yl)quinuclidine: Preparation and muscarinic receptor affinities
    Johansson, G
    Brisander, M
    Sundquist, S
    Hacksell, U
    CHIRALITY, 1998, 10 (09) : 813 - 820
  • [42] Synthesis, anti-inflammatory, antiplatelet and in silico evaluations of (E)-3-(3-(2,3-dihydro-3-methyl-2-oxo-3H-benzoxazole-6-yl)-1-phenyl-1H-pyrazole-4-yl)acrylamides
    Baytas, Sultan
    Dural, Nilufer Nermin Turan
    Ozkan, Yesim
    Simsek, Hasan Bolkan
    Gursel, Turkiz
    Unlu, Serdar
    TURKISH JOURNAL OF CHEMISTRY, 2012, 36 (03) : 367 - 382
  • [43] 2-[3-(Pyridin-1-ium-2-yl)-1H-pyrazol-1yl]-6-[3-(pyridin-2-yl)-1H-pyrazol-1-yl]pyridinium sulfate methanol monosolvate
    Huang, Linxia
    Shu, Mouhai
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O689 - +
  • [44] SYNTHESIS OF 3-(6-ALKYLAMINOPURIN-9-YL)-2,3-DIDEOXY-D-THREO-PENTOPYRANOSES AND THEIR REDUCTION TO 3-(6-ALKYLAMINOPURIN-9-YL)-2,3-DIDEOXY-D-THREO-PENTITOLS
    HJULERNIELSEN, HP
    PEDERSEN, H
    HANSEN, HB
    PEDERSEN, EB
    NIELSEN, C
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1992, 29 (02) : 511 - 513
  • [45] SYNTHESIS OF 3-(ALDITOL-1-YL)TRIAZOLO(4',3'-2,3)-1,2,4-TRIAZINO(5,6-B)INDOLES
    MOUSAAD, A
    HAMID, HA
    ELNEMR, A
    ELASHRY, ESH
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1992, 65 (02) : 546 - 552
  • [46] 1-(Naphthalen-1-yl)-3-[(thiophen-2-yl)-carbonyl]thiourea
    Singh, Durga P.
    Pratap, Seema
    Gupta, Sushil K.
    Butcher, Ray J.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O2882 - +
  • [47] 3-(1-Hydroxy-2-phenylprop-2-en-1-yl)phenol
    Caracelli, Ignez
    Zukerman-Schpector, Julio
    Singh, Fateh V.
    Stefani, Helio A.
    Tiekink, Edward R. T.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O1033 - U1438
  • [48] SYNTHESIS OF 3-(2,3-DIHYDROPYRAZOLE-3-ON-5-YL)-4-METHYL-5-ARYLPYRAZOLES
    ANDREICHIKOV, YS
    KOZMINYKH, EN
    KOZMINYKH, VO
    ZHURNAL ORGANICHESKOI KHIMII, 1985, 21 (10): : 2241 - 2242
  • [49] 3-[(Furan-2-yl)carbonyl]-1-(pyrimidin-2yl)thiourea
    Singh, Durga P.
    Pratap, Seema
    Gupta, Sushil K.
    Butcher, Ray J.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O3300 - +
  • [50] In Vitro and InSilico Evaluation of 2-(1H-Benzo[d]imidazol-2-yl)-3-(4-(piperazin-1-yl)phenyl)propanenitrile as Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
    Sarita, K.
    Kumar, N.
    Agrawal, A.
    Mali, S. N.
    Sharma, S.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2024, 50 (04) : 1563 - 1572
12345