RESPONSE TO HAEMOPHILUS-INFLUENZAE TYPE-B CONJUGATE VACCINE IN CHRONICALLY ILL PREMATURE-INFANTS

被引：33

作者：

WASHBURN, LK ^{[1
]}

OSHEA, TM ^{[1
]}

GILLIS, DC ^{[1
]}

BLOCK, SM ^{[1
]}

ABRAMSON, JS ^{[1
]}

机构：

[1] WAKE FOREST UNIV, BOWMAN GRAY SCH MED, DEPT PEDIAT, MED CTR BLVD, WINSTON SALEM, NC 27157 USA

来源：

JOURNAL OF PEDIATRICS | 1993年 / 123卷 / 05期

关键词：

D O I：

10.1016/S0022-3476(05)80862-5

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Twenty-two premature infants with chronic lung disease (median gestational age 28 weeks) received polyribosylribitol phosphate-outer membrane protein conjugate Haemophilus vaccine at 2 and 4 months of chronologic age. The proportions with antibodies to polyribosylribitol phosphate of levels >1 mug/ml after doses 1 and 2 were 27% and 55%; geometric mean titers were 0.43 and 0.73 mug/ml, significantly lower than values for term infants.

引用

页码：791 / 794

页数：4

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