LACK OF PHARMACOKINETIC INTERACTIONS BETWEEN MOXONIDINE AND DIGOXIN

被引：6
|
作者：
PABST, G
WEIMANN, HJ
WEBER, W
机构：
[1] KALI CHEM PHARMA GMBH, POB 220, W-3000 HANNOVER 1, GERMANY
[2] LAB GMBH & CO, NEU ULM, GERMANY
来源：
CLINICAL PHARMACOKINETICS | 1992年 / 23卷 / 06期
关键词：
D O I：
10.2165/00003088-199223060-00007
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The potential for pharmacokinetic interactions between moxonidine and digoxin at steady-state was investigated in 15 healthy male volunteers. Multiple oral doses of 0.2mg moxonidine twice daily and 0.2mg digoxin once daily were administered alone and in combination in a randomised 3-period crossover design. The drugs were administered for at least 5 days. The results indicate that neither moxonidine nor digoxin influences the pharmacokinetics of the other drug under steady-state conditions.
引用
收藏
页码：477 / 481
页数：5
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