STRIATAL CHOLINERGIC ACTIVITY DURING MORPHINE-INDUCED CATALEPSY IN THE RAT - DEVELOPMENT OF TOLERANCE

被引：6
|
作者：
ROSE, R [1 ]
KUMAR, A [1 ]
BHATTACHARYA, SK [1 ]
机构：
[1] BANARAS HINDU UNIV, INST MED SCI, DEPT PHARMACOL, NEUROPHARMACOL LAB, VARANASI 221005, UTTAR PRADESH, INDIA
来源：
NEUROSCIENCE LETTERS | 1979年 / 14卷 / 01期
关键词：
D O I：
10.1016/0304-3940(79)95355-2
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Morphine hydrochloride (10 mg/kg, i.p.) induced marked catalepsy in rats, which was associated with significantly enhanced striatal acetylcholine levels and reduced cholinesterase activity. Rapid tolerance to morphine-induced catalepsy was noted after twice daily administrations, the tolerance being discernible after the third injection and was complete after the eleventh injection. With the development of tolerance, morphine-induced effects on striatal acetylcholine and cholinesterase were progressively reversed, confirming striatal cholinergic involvement in morphine-induced catalepsy in the rat. © 1979.
引用
收藏
页码：115 / 118
页数：4
相关论文
共 50 条
  • [31] BRAIN CHOLINERGIC INVOLVEMENT DURING THE RAPID DEVELOPMENT OF TOLERANCE TO MORPHINE
    WAHBA, ZZ
    ORIAKU, ET
    SOLIMAN, KFA
    PHARMACOLOGY, 1987, 34 (2-3) : 66 - 73
  • [32] Effect of adenosine receptor agonists and antagonists on morphine-induced catalepsy In mice
    Zarrindast, MR
    Iraie, F
    Heidari, MR
    MohagheghiBadi, M
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1997, 338 (01) : 11 - 16
  • [33] Midbrain muscarinic receptors modulate morphine-induced accumbal and striatal dopamine efflux in the rat
    Miller, AD
    Forster, GL
    Yeomans, JS
    Blaha, CD
    NEUROSCIENCE, 2005, 136 (02) : 531 - 538
  • [34] REM-SLEEP DEPRIVATION ANTAGONIZES MORPHINE-INDUCED AKINESIA AND CATALEPSY
    UKPONMWAN, OE
    VANDERPOELHEISTERKAMP, AL
    DZOLJIC, MR
    SLEEP, 1986, 9 (03) : 415 - 422
  • [35] Vigabatrin attenuates the development and expression of tolerance to morphine-induced antinociception in mice
    Chavooshi, Behzad
    Saberi, Mehdi
    Tehrani, Said Pournaghash
    Bakhtiarian, Azam
    Ahmadiani, Abolhassan
    Haghparast, Abbas
    PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2009, 93 (02) : 155 - 159
  • [36] Role of the cholinergic system in the rat basolateral amygdala on morphine-induced conditioned place preference
    Zarrindast, MR
    Fattahi, Z
    Rostami, P
    Rezayof, A
    PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2005, 82 (01) : 1 - 10
  • [37] EFFECTS OF LEVETIRACETAM ON THE DEVELOPMENT AND EXPRESSION OF TOLERANCE TO MORPHINE-INDUCED ANTINOCICEPTION IN MICE
    Vesali, R.
    Saberi, M.
    Hassantash, M. H.
    Tehrani, S. P.
    EUROPEAN PSYCHIATRY, 2012, 27
  • [38] THE CHOLINERGIC SYSTEM IN RAT STRIATUM DURING MORPHINE-TOLERANCE AND DEPENDENCE
    SCHURR, A
    RIGOR, BM
    STRONG, R
    GOTTESFELD, Z
    LIFE SCIENCES, 1983, 33 (25) : 2521 - 2525
  • [39] EFFECT OF CYCLO(LEU-GLY) ON CYCLIC GMP-PHOSPHODIESTERASE ACTIVITY CHANGES ASSOCIATED WITH DEVELOPMENT OF TOLERANCE TO MORPHINE-INDUCED ANTINOCICEPTION, CATALEPSY, RESPIRATORY DEPRESSION AND MYDRIASIS
    BURTON, CK
    HO, IK
    HOSKINS, B
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1991, 258 (03) : 871 - 876
  • [40] Role of spinal metabotropic glutamate receptor subtype 5 in the development of tolerance to morphine-induced antinociception in rat
    Xu, Tao
    Jiang, Wei
    Du, Dongping
    Xu, Yongming
    Hu, Qian
    Shen, Qin
    NEUROSCIENCE LETTERS, 2007, 420 (02) : 155 - 159
12345