OPTICAL ABSORBANCE AND OPTICAL ROTATORY DISPERSION STUDIES ON CALF THYMUS NUCLEOHISTONE

被引：127
|
作者：
TUAN, DYH
BONNER, J
机构：
[1] Division of Biology, California Institute of Technology Pasadena, CA
来源：
JOURNAL OF MOLECULAR BIOLOGY | 1969年 / 45卷 / 01期
关键词：
D O I：
10.1016/0022-2836(69)90209-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Optical absorption and optical rotatory dispersion studies of native nucleohistone and of nucleohistone fully or partially and selectively dissociated into DNA and histone, show that (1) the conformation of whole histone mixtures as well as of individual histone fractions is highly ionic strength dependent and that the conformation of histone in association with DNA approximates that of free histone in solutions of high ionic strength; (2) the conformation of DNA in native nucleohistone is altered as compared to free DNA; and (3) neither lysinerich histone I nor non-histone protein is responsible for the conformational characteristics of DNA in nucleohistone. © 1969.
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页码：59 / &
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