PREGNANCY OUTCOME AND INFANT-MORTALITY IN DIABETIC-PATIENTS IN SWEDEN

被引：23

作者：

CNATTINGIUS, S

BERNE, C

NORDSTROM, ML

机构：

[1] Departments of Social Medicine, University Hospital, Uppsala University, Uppsala

[2] Departments of Internal Medicine, University Hospital, Uppsala University, Uppsala

来源：

DIABETIC MEDICINE | 1994年 / 11卷 / 07期

关键词：

DIABETES-MELLITUS; PREGNANCY; FETAL DEATH; INFANT DEATH; CONGENITAL MALFORMATIONS;

D O I：

10.1111/j.1464-5491.1994.tb00335.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Between 1983 and 1986, 914 single births to women with diabetes mellitus before pregnancy and a randomly selected control sample of 4000 births were identified by using the Swedish Medical Birth Registry. Twenty-four percent of diabetic women were delivered preterm, as compared with 6 % in the control group. The rates of late fetal death were a 1.3 % among infants born to women with diabetes and 0.4 % in the control group. Infant mortality was 0.9 % and 0.5 % among infants to mothers with and without diabetes mellitus, respectively. The increased rates of late fetal and infant deaths in the diabetes group were largely explained by higher mortality in the more prevalent preterm deliveries. Fourteen of 20 late fetal and infant deaths occurred among preterm infants in diabetic pregnancies, while in the control group, 17 of 33 late fetal and infant deaths occurred among preterm infants. Elimination of the increased rates of late fetal death and congenital malformation in diabetic pregnancy is required to meet the goals of the St Vincent Declaration. A nation-wide registry of diabetic pregnancy outcomes is feasible and necessary for further quality assurance of diabetic pregnancies.

引用

页码：696 / 700

页数：5

共 24 条

[1] Perinatal mortality and congenital malformations in infants born to women with insulin‐dependent diabetes mellitus‐United States, Canada and Europe 1940–1988, J Am Med Assoc, 264, pp. 437-440, (1990)
[2] Connell FA, Vadheim C., Emanuel I., Diabetes in pregnancy: A population‐based study of incidence, referral for care and perinatal mortality, Am J Obstet Gynecol, 151, pp. 598-603, (1985)
[3] Warram JH, Krolewski AS, Kahn CR, Determinants of IDDM and perinatal mortality in children of diabetic mothers, Diabetes, 37, pp. 1328-1334, (1988)
[4] Olofsson P., Liedholm H., Sartor G., Sjoberg NO, Svenningsen NW, Ursing D., Diabetes and pregnancy. A 21‐year Swedish material, Acta Obstet Gynecol Scand, (1984)
[5] Multicenter survey of diabetes in France, Diabetes Care, 14, pp. 994-1000, (1991)
[6] Cousins L., The California diabetes and pregnancy programme: a statewide collaborative programme for preconception and prenatal care of diabetic women, Clinics Obstet Gynecol, 5, pp. 443-459, (1991)
[7] Damm P., Molsted-Pedersen L., Significant decrease in congenital malformations in newborn infants of an unselected population of diabetic women, Am J Obstet Gynecol, 161, pp. 1163-1167, (1989)
[8] Mills JL, Knopp RH, Simpson JL, Jovanovic-Peterson L., Metzger BE, Holmes LB, Et al., Lack of relation of increased congenital malformation rates in infants of diabetic mothers to metabolic control during organogenesis, New Engl J Med, 318, pp. 671-676, (1988)
[9] Diabetes care and research in Europe: The St Vincent Declaration, Diabetic Med, 7, (1990)
[10] Lindmark G., Cnattingius S., The scientific basis of antenatal care. Report from a state‐of‐the‐art conference, Acta Obstet Gynecol Scand, 70, pp. 105-109, (1991)

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