ENZYME ASSISTED SYNTHESIS OF ENANTIOMERICALLY PURE MYOINOSITOL DERIVATIVES - CHIRAL BUILDING-BLOCKS FOR INOSITOL POLYPHOSPHATES

被引：46

作者：

ANDERSCH, P ^{[1
]}

SCHNEIDER, MP ^{[1
]}

机构：

[1] BERG UNIV GESAMTHSCH WUPPERTAL,FB 9,D-42097 WUPPERTAL,GERMANY

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 10期

关键词：

D O I：

10.1016/S0957-4166(00)80058-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Using a short and facile synthetic protocol involving highly selective, regio- and enantioselective enzymatic esterifications as key reaction steps, readily available myo -inositol is converted into optically pure 1D-1-O-butyryl-4,6-O-dibenzoyl-myo-inositol (-) - 5, a selectively protected central intermediate for the preparation of numerous inositol phosphates.

引用

页码：2135 / 2138

页数：4