ENZYME ASSISTED SYNTHESIS OF ENANTIOMERICALLY PURE MYOINOSITOL DERIVATIVES - CHIRAL BUILDING-BLOCKS FOR INOSITOL POLYPHOSPHATES

被引:46
作者
ANDERSCH, P [1 ]
SCHNEIDER, MP [1 ]
机构
[1] BERG UNIV GESAMTHSCH WUPPERTAL,FB 9,D-42097 WUPPERTAL,GERMANY
关键词
D O I
10.1016/S0957-4166(00)80058-0
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Using a short and facile synthetic protocol involving highly selective, regio- and enantioselective enzymatic esterifications as key reaction steps, readily available myo -inositol is converted into optically pure 1D-1-O-butyryl-4,6-O-dibenzoyl-myo-inositol (-) - 5, a selectively protected central intermediate for the preparation of numerous inositol phosphates.
引用
收藏
页码:2135 / 2138
页数:4
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