The GEM Project: Stool metabolomic profile is associated with microbiome risk score and with future onset of Crohn's disease in healthy first-degree relatives

被引：0

作者：

Lee, S. H. ^{[1
]}

Garay, J. A. Raygoza ^{[1
]}

Turpin, W. ^{[1
]}

Smith, M. I. ^{[1
]}

Goethel, A. ^{[1
]}

Griffiths, A. ^{[2
]}

Moayyedi, P. ^{[3
]}

Espin-Garcia, O. ^{[4
]}

Abreu, M. ^{[5
]}

Aumais, G. ^{[6
]}

Bernstein, C. N. ^{[7
]}

Biron, I. ^{[8
]}

Cino, M. ^{[9
]}

Deslandres, C. ^{[10
]}

Dotan, I. ^{[8
]}

El-Matary, W.

Feagan, B. ^{[11
,12
,13
]}

Guttman, D. ^{[14
]}

Huynh, H. ^{[15
]}

Hyams, J. ^{[16
]}

Jacobson, K. ^{[17
]}

Mack, D. ^{[18
,19
]}

Marshall, J.

Otley, A. ^{[20
]}

Panaccione, R. ^{[21
]}

Ropeleski, M. ^{[22
]}

Silverberg, M. S. ^{[1
]}

Steinhart, A. H. ^{[1
]}

Turner, D. ^{[23
]}

Yerushalmi, B. ^{[24
,25
]}

Xu, W. ^{[4
]}

Croitoru, K. ^{[1
]}

机构：

[1] Univ Toronto, Mt Sinai Hosp, Div Gastroenterol, Toronto, ON, Canada

[2] Hosp Sick Children, Div Gastroenterol, Toronto, ON, Canada

[3] McMaster Univ, Farncombe Family Digest Hlth Res Inst, Dept Med, Hamilton, ON, Canada

[4] Univ Toronto, Div Biostat, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[5] Univ Miami, Miller Sch Med, Dept Med, Div Gastroenterol, Miami, FL USA

[6] Hop Maison Neuve Rosemont, Dept Gastroenterol, Montreal, PQ, Canada

[7] Univ Manitoba, Inflammatory Bowel Dis Clin & Res Ctr, Winnipeg, MB, Canada

[8] Univ Toronto, Div Gastroenterol & Hepatol, Toronto, ON, Canada

[9] CHU St Justine, Dept Gastroenterol, Montreal, PQ, Canada

[10] Univ Manitoba, Pediat Gastroenterol, Winnipeg, MB, Canada

[11] Univ Western Ontario, Dept Med, London, ON, Canada

[12] Univ Western Ontario, Dept Epidemiol, London, ON, Canada

[13] Univ Western Ontario, Dept Biostat, London, ON, Canada

[14] Univ Toronto, Ctr Anal Genome Evolut & Funct, Toronto, ON, Canada

[15] Univ Alberta, Dept Pediat, Edmonton, AB, Canada

[16] Connecticut Childrens Med Ctr, Div Digest Diseases Hepatol & Nutr, Hartford, CT USA

[17] British Columbia Childrens Hosp, Dept Pediat, Vancouver, BC, Canada

[18] Childrens Hosp Eastern Ontario, Ottawa, ON, Canada

[19] Univ Ottawa, Div Gastroenterol Hepatol & Nutr, Ottawa, ON, Canada

[20] Dalhousie Univ, Div Gastroenterol, Izaak Walton Killam Hosp, Halifax, NS, Canada

[21] Univ Calgary, Dept Gastroenterol, Calgary, AB, Canada

[22] Queens Univ, Gastrointestinal Dis Res Unit, Dept Med, Kingston, ON, Canada

[23] Hebrew Univ Jerusalem, Juliet Keidan Inst Pediat Gastroenterol & Nutr, Shaare Zedek Med Ctr, Jerusalem, Israel

[24] Soroka Univ, Med Ctr, Beer Sheva, Israel

[25] Ben Gurion Univ Negev, Fac Hlth Sci, Pediat Gastroenterol Unit, Beer Sheva, Israel

来源：

JOURNAL OF CROHNS & COLITIS | 2022年 / 16卷

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

P700

引用

页码：I596 / I597

页数：2

共 50 条

[21] Small intestinal permeability in patients with Crohn's disease and their first-degree relatives.
Song, IS
Lee, CH
Jung, HC
Kim, CY
GASTROENTEROLOGY, 1998, 114 (04) : A1088 - A1088
[22] Enhanced microbiota profiling in patients with quiescent Crohn's disease through comparison with paired healthy first-degree relatives
Chen, Wanning
Li, Yichen
Wang, Wenxia
Gao, Sheng
Hu, Jun
Xiang, Bingjie
Wu, Dingfeng
Jiao, Na
Xu, Tao
Zhi, Min
Zhu, Lixin
Zhu, Ruixin
CELL REPORTS MEDICINE, 2024, 5 (07)
[23] Increased Frequency of Risk Alleles in a Cohort of Healthy First Degree Relatives of Crohn's Disease Patients - A Report Front the Michael J. Howorth/CCFC GEM Project
Silverberg, Mark S.
Xu, Wei
Paterson, Andrew D.
Croitoru, Ken
GASTROENTEROLOGY, 2011, 140 (05) : S268 - S268
[24] Tissue Studies in Screened First-degree Relatives Reveal a Distinct Crohn's Disease Phenotype
Sorrentino, Dario
Avellini, Claudio
Geraci, Marco
Dassopoulos, Themistocles
Zarifi, Dimitra
di Prampero, Salvatore Francesco Vadala'
Benevento, Gianluca
INFLAMMATORY BOWEL DISEASES, 2014, 20 (06) : 1049 - 1056
[25] DETERMINING ASSOCIATIONS BETWEEN DIETARY INTAKE AND INTESTINAL PERMEABILITY (IP) IN HEALTHY FIRST-DEGREE RELATIVES OF CROHN'S DISEASE PATIENTS
Howarth, N.
Turpin, W.
Smith, M.
Croitoru, K.
IRISH JOURNAL OF MEDICAL SCIENCE, 2017, 186 : S30 - S30
[26] Genetic and environmental risk model to predict intestinal inflammation in asymptomatic first-degree relatives of Crohn's disease patients
Taylor, K. M.
Taylor, N. S.
Anderson, S. H.
Irving, P. M.
Prescott, N. J.
Lewis, C. M.
Mathew, C. G.
Sanderson, J. D.
JOURNAL OF CROHNS & COLITIS, 2016, 10 : S26 - S26
[27] Determinants of Intestinal Permeability in Healthy First-degree Relatives of Individuals with Crohn's Disease (vol 21, pg 879, 2015)
Kevans, D.
Turpin, W.
Madsen, K.
INFLAMMATORY BOWEL DISEASES, 2015, 21 (07) : 1673 - 1673
[28] Genetic and Environmental Risk Model to Predict Intestinal Inflammation in Asymptomatic First-Degree Relatives of Crohn's Disease Patients
Taylor, Kirstin M.
Taylor, Nicola S.
Anderson, Simon H.
Irving, Peter M.
Prescott, Natalie J.
Lewis, Cathryn M.
Mathew, Christopher
Sanderson, Jeremy D.
GASTROENTEROLOGY, 2016, 150 (04) : S548 - S548
[29] Increased risk of breast cancer in first-degree relatives of Crohn's disease patients - An IG-IBD study
Riegler, G
Caserta, L
Castiglione, F
Esposito, I
Valpiani, D
Annese, V
Zoli, G
Gionchetti, P
Viscido, A
Sturniolo, GC
Rispo, A
De Filippo, FR
de Leone, A
Carratu, R
DIGESTIVE AND LIVER DISEASE, 2006, 38 (01) : 18 - 23
[30] Microbiome Profiling of Flora Adhering to the Gut Wall in Crohn's Disease and First Degree Relatives
Kuballa, Anna
Sorrentino, Dario
GASTROENTEROLOGY, 2016, 150 (04) : S577 - S577

← 1 2 3 4 5 →