SYNTHESIS AND CHARACTERIZATION OF NOVEL BIOLOGICALLY-ACTIVE PLATINUM(II) AND PALLADIUM(II) COMPLEXES OF SOME BETA-CARBOLINE ALKALOIDS

被引：37

作者：

ALALLAF, TAK ^{[1
]}

AYOUB, MT ^{[1
]}

RASHAN, LJ ^{[1
]}

机构：

[1] UNIV MOSUL,COLL EDUC,DEPT BIOL,MOSUL,IRAQ

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 1990年 / 38卷 / 01期

关键词：

D O I：

10.1016/0162-0134(90)85006-I

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The preparation of novel biologically active platinum(II) and palladium(II) complexes of some β-carboline alkaloids (harmaline, harmalol, harmine, and harmane) is described. These complexes, characterized on the basis of their CHN elemental analysis, infrared, Raman, and 1H and 13C nuclear magnetic resonance spectral data, were shown to have the empirical formula [M(alkaloid)Cl2], M = Pt, Pd. The antitumor and antiviral activities of some of these complexes have been demonstrated. © 1990.

引用

页码：47 / 56

页数：10

共 20 条

[1] SYNTHESIS AND NMR ASSIGNMENTS OF SOME PLATINUM(II) COMPLEXES OF 3-ARYL-5,5-DIMETHYL-2-PYRAZOLINES [J].