METHODS FOR THE DETECTION OF APOPTOSIS

被引:125
作者
SGONC, R
WICK, G
机构
[1] Inst. General Experimental Pathology, University Innsbruck Medical School, A-6020 Innsbruck
关键词
APOPTOSIS; CONFOCAL LASER SCAN MICROSCOPY; FLOW CYTOMETRY; 3'-OH END LABELING; TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE MEDIATED DUTP NICK END LABELING (TUNEL);
D O I
10.1159/000236777
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Apoptosis is central to many basic and clinically oriented investigations, and this article is a brief overview of the most frequently utilized methods for detection of apoptotic cells, including the study of morphology, analysis of DNA degradation, DNA end labeling techniques, flow cytometric analysis, and nuclease assays. Features and advantages ofthe different methods are discussed.
引用
收藏
页码:327 / 332
页数:6
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