ANIONIC PHOSPHOLIPID;
PROTEIN INSERTION AND TRANSLOCATION;
PROTEIN FOLDING;
LIPID-PROTEIN INTERACTION;
TARGETING SIGNAL;
D O I:
10.1016/0014-5793(94)00404-8
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
Anionic phospholipids determine, in diverse ways, the membrane interaction of proteins involved in or undergoing membrane insertion or translocation. How these lipids modulate protein localization, organization, folding and membrane insertion is herein summarized and generalized, leading to a proposal for the function of anionic lipids in cellular transport of newly synthesized proteins.