LOW-DENSITY-LIPOPROTEIN IMMUNOFLUORESCENCE AT THE SITE OF RENAL INJURY IN GLOMERULOSCLEROSIS - A POTENTIAL PATHOGENETIC ROLE FOR LIPIDS IN RENAL-DISEASE

被引：9
作者：
AVRAM, MM
机构：
[1] Division of Nephrology, Long Island College Hospital, Brooklyn, New York
来源：
AMERICAN JOURNAL OF KIDNEY DISEASES | 1993年 / 22卷 / 01期
关键词：
CHOLESTEROL; LOW-DENSITY LIPOPROTEIN IMMUNOFLUORESCENCE; GLOMERULOSCLEROSIS; VASOACTIVE AGENTS; PREALBUMIN; RENAL FAILURE MALNUTRITION;
D O I：
10.1016/S0272-6386(12)70170-1
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The role of lipids in the genesis of renal disease has received increased attention. We describe the presence of anti-low-density lipoprotein immunofluorescence at the site of renal injury found by light microscopy. This may offer immunohistologic evidence for a potential role of this atherogenic lipid in the genesis of renal disease and glomerulosclerosis. Furthermore, we describe the contribution of cholesterol in early renal disease and markers for malnutrition in the dialytic management of end-stage renal disease. Interventional strategies, including vasoactive agents present and future, are presented. © 1993, National Kidney Foundation. All rights reserved. All rights reserved.
引用
收藏
页码：69 / 71
页数：3
相关论文
共 32 条
[1]  
ANDERSON S, 1989, AM J MED, V87, P34
[2]  
AVRAM MM, 1989, AM J MED, V87, P39
[3]  
AVRAM MM, 1992, AM J KIDNEY DIS, V20, P624
[4]   RENAL PROTECTIVE EFFECT OF ENALAPRIL IN DIABETIC NEPHROPATHY [J].
BJORCK, S ;
MULEC, H ;
JOHNSEN, SA ;
NORDEN, G ;
AURELL, M .
BMJ-BRITISH MEDICAL JOURNAL, 1992, 304 (6823) :339-343
[5]   IMPAIRED VASODILATION OF FOREARM RESISTANCE VESSELS IN HYPERCHOLESTEROLEMIC HUMANS [J].
CREAGER, MA ;
COOKE, JP ;
MENDELSOHN, ME ;
GALLAGHER, SJ ;
COLEMAN, SM ;
LOSCALZO, J ;
DZAU, VJ .
JOURNAL OF CLINICAL INVESTIGATION, 1990, 86 (01) :228-234
[6]   LIPOPROTEIN(A) IS AN INDEPENDENT RISK FACTOR FOR CARDIOVASCULAR-DISEASE IN HEMODIALYSIS-PATIENTS [J].
CRESSMAN, MD ;
HEYKA, RJ ;
PAGANINI, EP ;
ONEIL, J ;
SKIBINSKI, CI ;
HOFF, HF .
CIRCULATION, 1992, 86 (02) :475-482
[7]  
DAMICO G, 1993, AM J KIDNEY DIS, V21, P151
[8]  
GOLDWASSER P, 1993, J AM SOC NEPHROL, V3, P1613
[9]  
GOLDWASSER P, 1993, AM J KIDNEY DIS, V21, P215
[10]   LOVASTATIN AMELIORATES THE DEVELOPMENT OF GLOMERULOSCLEROSIS AND UREMIA IN EXPERIMENTAL NEPHROTIC SYNDROME [J].
HARRIS, KPG ;
PURKERSON, ML ;
YATES, J ;
KLAHR, S .
AMERICAN JOURNAL OF KIDNEY DISEASES, 1990, 15 (01) :16-23
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