A facile one-pot synthesis of 3-(1-Benzyl-2-phenyl-1H-imidazol-4-yl)-4-hydroxy-6-methyl-2H-pyran-2-one derivatives via multi-component approach

被引:0
作者
Bade, Thirupaiah [1 ]
Vedula, Rajeswar Rao [1 ]
机构
[1] Natl Inst Technol, Dept Chem, Warangal 506004, Andhra Prades, India
关键词
bromo dehydroacetic acid; aromatic aldehyde; benzyl amine; ammonium acetate; imidazole; one-pot; multi component reactions;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A one pot, four component synthesis of 1, 2, 4-trisubstituted imidazoles is described by reacting a mixture of bromo dehydroacetic acid, aromatic aldehyde, benzyl amine, and ammonium acetate in dry alcohol. All the synthesized compounds were characterized by their analytical and spectral data.
引用
收藏
页码:53 / 59
页数:7
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共 37 条
  • [1] In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives
    Achar, Kavitha C. S.
    Hosamani, Kallappa M.
    Seetharamareddy, Harisha R.
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (05) : 2048 - 2054
  • [2] 4-hydroxy-6-methyl-3-(5-phenyl-2E,4E-pentadien-1-oyl)-2H-pyran-2-one:: Synthesis and reactivity with amines
    Aït-Baziz, N
    Rachedi, Y
    Hamdi, M
    Silva, AMS
    Balegroune, F
    Thierry, R
    Sellier, N
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2004, 41 (04) : 587 - 591
  • [3] Anshul C., 2012, PHARM CHEM, V4, P116
  • [4] Bienayme H, 2000, CHEM-EUR J, V6, P3321, DOI 10.1002/1521-3765(20000915)6:18<3321::AID-CHEM3321>3.0.CO
  • [5] 2-A
  • [6] Drugs acting on imidazoline receptors - A review of their pharmacology, their use in blood pressure control and their potential interest in cardioprotection
    Bousquet, P
    Feldman, J
    [J]. DRUGS, 1999, 58 (05) : 799 - 812
  • [7] COREY EJ, 1999, J ORG LETT, V1, P157
  • [8] Dandale S. G., 2012, International Journal of Research in Pharmaceutical and Biomedical Sciences, V3, P780
  • [9] Potent, orally absorbed glucagon receptor antagonists
    de Laszlo, SE
    Hacker, C
    Li, B
    Kim, D
    MacCoss, M
    Mantlo, N
    Pivnichny, JV
    Colwell, L
    Koch, GE
    Cascieri, MA
    Hagmann, WK
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (05) : 641 - 646
  • [10] Recent developments in isocyanide based multicomponent reactions in applied chemistry
    Dömling, A
    [J]. CHEMICAL REVIEWS, 2006, 106 (01) : 17 - 89