Pressure ulcer healing with Plenusdermax((R)) Calendula officinalis L. extract

Objective: to evaluate the therapeutic benefits of the bioactive extracts of Plenusdermax (R) Calendula officinalis for pressure ulcer healing. Method: an observational cohort study, including 41 patients with a diagnosis of pressure ulcer that was stable in size for more than three months. Patients were evaluated every two weeks, over 30 weeks, for: reduction of the wound area, infection control, types of tissue and exudate, and ulcer microbiology. Results: the proportions of patients who were completely healed after 15 and 30 weeks of treatment were 63% and 88%, respectively, and the mean healing time was 12.5 +/- 7.8 weeks. No adverse events were observed during treatment. Conclusion: the results of the study indicate that bioactive C. officinalis Plenusdermax (R) is a safe treatment that promotes healing of pressure ulcers.