NEOMYCIN CANNOT BE USED AS A SELECTIVE INHIBITOR OF INOSITOL PHOSPHOLIPID HYDROLYSIS IN INTACT OR SEMI-PERMEABILIZED HUMAN-PLATELETS - AMINOGLYCOSIDES ACTIVATE SEMI-PERMEABILIZED PLATELETS

被引：29

作者：

POLASCIK, T ^{[1
]}

GODFREY, PP ^{[1
]}

WATSON, SP ^{[1
]}

机构：

[1] RADCLIFFE INFIRM,DEPT CLIN PHARMACOL,OXFORD OX2 6HE,ENGLAND

来源：

BIOCHEMICAL JOURNAL | 1987年 / 243卷 / 03期

关键词：

D O I：

10.1042/bj2430815

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：815 / 819

页数：5

共 29 条

[1] METABOLIC AND FUNCTIONAL CONSEQUENCES OF INTRODUCING INOSITOL 1,4,5-TRISPHOSPHATE INTO SAPONIN-PERMEABILIZED HUMAN-PLATELETS [J].

AUTHI, KS ;

EVENDEN, BJ ;

CRAWFORD, N .

BIOCHEMICAL JOURNAL, 1986, 233 (03) :707-718

[2] INOSITOL TRISPHOSPHATE, A NOVEL 2ND MESSENGER IN CELLULAR SIGNAL TRANSDUCTION [J].

BERRIDGE, MJ ;

IRVINE, RF .

NATURE, 1984, 312 (5992) :315-321

[3]

BRASS LF, 1985, J BIOL CHEM, V260, P5172

[4] PHOSPHOINOSITIDES IN MITOGENESIS - NEOMYCIN INHIBITS THROMBIN-STIMULATED PHOSPHOINOSITIDE TURNOVER AND INITIATION OF CELL-PROLIFERATION [J].

CARNEY, DH ;

SCOTT, DL ;

GORDON, EA ;

LABELLE, EF .

CELL, 1985, 42 (02) :479-488

[5] ROLE OF GUANINE-NUCLEOTIDE BINDING-PROTEIN IN THE ACTIVATION OF POLYPHOSPHOINOSITIDE PHOSPHODIESTERASE [J].

COCKCROFT, S ;

GOMPERTS, BD .

NATURE, 1985, 314 (6011) :534-536

[6]

DOWNES CP, 1985, MOL ASPECTS CELLULAR, V4, P3

[7] ACTIVATION OF HUMAN-PLATELETS BY ADP CAUSES A RAPID RISE IN CYTOSOLIC FREE CALCIUM WITHOUT HYDROLYSIS OF PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE [J].

FISHER, GJ ;

BAKSHIAN, S ;

BALDASSARE, JJ .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 129 (03) :958-964

[8] EFFECTS OF NEOMYCIN ON CALCIUM AND POLYPHOSPHINOSITIDE METABOLISM OF GUINEA-PIG SYNAPTOSOMES [J].

GRIFFIN, HD ;

SYKES, M ;

HAWTHORNE, JN .

JOURNAL OF NEUROCHEMISTRY, 1980, 34 (03) :750-752

[9]

KAIBUCHI K, 1983, J BIOL CHEM, V258, P6701

[10] EFFECT OF NEOMYCIN AND IONOPHORE A23187 ON ATP LEVELS AND TURNOVER OF POLYPHOSPHOINOSITIDES IN HUMAN ERYTHROCYTES [J].

LANG, V ;

PRYHITKA, G ;

BUCKLEY, JT .

CANADIAN JOURNAL OF BIOCHEMISTRY, 1977, 55 (09) :1007-1012

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