CORTICAL SLOW POTENTIAL CHANGES DURING CONVULSIONS INDUCED BY MAXIMAL ELECTROSHOCK OR PENICILLIN FOCUS

被引：6

作者：

DEAZEREDO, FAM ^{[1
]}

PERRET, ML ^{[1
]}

机构：

[1] UNIV FED FLUMINENSE,INST BIOL,BIOCIENCIAS LAB,BR-24000 NITEROI,RJ,BRAZIL

来源：

METABOLIC BRAIN DISEASE | 1992年 / 7卷 / 02期

关键词：

SPREADING DEPRESSION; MULTIFOCAL DEPRESSION; SLOW POTENTIALS; EPILEPTIC FOCUS; MAXIMAL ELECTROSHOCK;

D O I：

10.1007/BF01000149

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We have described the occurrence in freely moving gerbils of slow potential changes (SPC) in two different models of experimental epilepsy: 1) maximal electroshock and 2) bilateral epileptic foci induced by penicillin.SPC is considered a by-product of epileptiform activity in both models and correlates to the SPC which occurs during spreading depression. In the first model there develops a cortical SPC simultaneous with a depression of EEG activity, although there is no propagation of the wave. We suggest that a non-propagated multifocal depression (MD) occurs in the MES model. In the model of focal epilepsy, all requirements are fulfilled, and the SPC is characterized as the one which occurs during spreading depression propagating with an average velocity of 8 mm/min.

引用

页码：101 / 133

页数：33

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