STEREOCONTROLLED FORMATION OF POLYSUBSTITUTED TETRAHYDROFURANS BY DEBENZYLATING CYCLOETHERIFICATION

被引：42

作者：

DEHMLOW, H

MULZER, J

SEILZ, C

STRECKER, AR

KOHLMANN, A

机构：

[1] Institut für Organische Chemie der Freien Universitat Berlin, W-1000 Berlin

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 25期

关键词：

TETRAHYDROFURAN; NEIGHBORING GROUP PARTICIPATION OF BENZYL ETHERS; MITSUNOBU CONDITIONS; SMALL RINGS; MESYLATES;

D O I：

10.1016/S0040-4039(00)92514-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzyl ethers with S(N)2 active sites in gamma-position undergo spontaneous regio- and stereocontrolled tetrahydrofuran cyclization with concomitant debenzylation even under mildly acidic or neutral conditions.

引用

页码：3607 / 3610

页数：4

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