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- [41] Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor AgonistJOURNAL OF MEDICINAL CHEMISTRY, 2015, 58 (18) : 7526 - 7548Monn, James A.Prieto, LourdesTaboada, LorenaHao, JunliangReinhard, Matthew R.Hen, Steven S.Beadle, Christopher D.Walton, LesleyMan, TeresaRudyk, HeleneClark, BarryTupper, DavidBaker, S. RichardLamas, CarlosMontero, CarlosMarcos, AliciaBlanco, JaimeBures, MarkClawson, David K.Atwell, ShaneLu, FrancesWang, JingRussell, MarijaneHeinz, Beverly A.Wang, XushanCarter, Joan H.Getman, Brian G.Catlow, John T.Swanson, StevenJohnson, Bryan G.Shaw, David B.McKinzie, David L.
- [42] Synthesis and Pharmacological Characterization of C4β-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1S,2S,4S,5R,6S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu3 Receptor AgonistJOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (06) : 2303 - 2328Monn, James A.Henry, Steven S.Massey, Steven M.Clawson, David K.Chen, QiDiseroad, Benjamin A.Bhardwaj, Rajni M.Atwel, ShaneLu, FrancesWang, JingRussell, MarijaneHeinz, Beverly A.Wang, Xu-shanCarter, Joan H.Getman, Brian G.Adragni, KofiBroad, Lisa M.Sanger, Helene E.Ursu, DanielCatlow, John T.Swanson, StevenJohnson, Bryan G.Shaw, David B.McKinzie, David L.Hao, Junliang