SOME ANALOGS OF 1,4-DISUBSTITUTED PIPERAZINES AS HYPNOTIC AND SEDATIVE AGENTS

被引：5
|
作者：
CHILMONCZYK, Z
BOGDAL, M
ZAWORSKA, A
CYBULSKI, J
SZELEJEWSKI, W
机构：
[1] Pharmaceutical Research Institute, Warszawa, 01-793
来源：
ARCHIV DER PHARMAZIE | 1995年 / 328卷 / 02期
关键词：
D O I：
10.1002/ardp.19953280218
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Preparation, analytical data, and biological properties such as acute toxicity, influence on spontaneous and amphetamine induced locomotor activity, hypnotic activity, influence on hexobarbital narcosis and anticonvulsant activity of new analogues of pyrimidyl piperazines - ethyl 3-[4-(2-pyrimidyl)-1-piperazinyl]-3-oxopropanoate (4), 1-[4-(2-pyrimidyl)-1-piperazinyl]-1,3-butandione (5), ethyl 3-[4-(2-pyrimidyl)-1-piperazinyl]butanoate (6) and 1-[4-(2-pyrimidyl)-1-piperazinyl]-2-acetyl-1-hexanone (7) are reported.
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页码：187 / 191
页数：5
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