INVITRO ANTIBACTERIAL ACTIVITY OF THE VOLATILE OIL OF NIGELLA-SATIVA SEEDS AGAINST MULTIPLE DRUG-RESISTANT ISOLATES OF SHIGELLA SPP AND ISOLATES OF VIBRIO-CHOLERAE AND ESCHERICHIA-COLI

被引：45

作者：

FERDOUS, AJ ^{[1
]}

ISLAM, SN ^{[1
]}

AHSAN, M ^{[1
]}

HASAN, CM ^{[1
]}

AHMED, ZU ^{[1
]}

机构：

[1] INT CTR DIARRHOEL DIS RES, DHAKA, BANGLADESH

来源：

PHYTOTHERAPY RESEARCH | 1992年 / 6卷 / 03期

关键词：

INVITRO; ANTIBACTERIAL; VOLATILE OIL; NIGELLA-SATIVA; RESISTANT ISOLATES;

D O I：

10.1002/ptr.2650060307

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antibacterial activity of the volatile oil of Nigella sativa seeds was studied against 37 isolates of Shigella dysenteriae 1, Shigella flexneri, Shigella sonnei and Shigella boydii and 10 strains of Vibrio cholerae and Escherichia coli. Most of the strains were clinically resistant to ampicillin, co-trimoxazole and tetracycline. All the strains tested showed promising sensitivity to the volatile oil. The minimum inhibitory concentration (MIC) of the volatile oil for Shigella, Vibrio and Escherichia strains tested was between 50-400-mu-g/mL.

引用

页码：137 / 140

页数：4

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