FREE-RADICALS INACTIVATE HUMAN NEUTROPHIL ELASTASE AND ITS INHIBITORS WITH COMPARABLE EFFICIENCY

被引:29
作者
DEAN, RT [1 ]
NICK, HP [1 ]
SCHNEBLI, HP [1 ]
机构
[1] CIBA GEIGY AG,CH-4002 BASEL,SWITZERLAND
关键词
D O I
10.1016/0006-291X(89)90068-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:821 / 827
页数:7
相关论文
共 31 条
[1]  
BAIRD B, 1986, J APPL PHYSIOL, V61, P225
[2]   REFINED 1.2-A CRYSTAL-STRUCTURE OF THE COMPLEX FORMED BETWEEN SUBTILISIN CARLSBERG AND THE INHIBITOR EGLIN-C - MOLECULAR-STRUCTURE OF EGLIN AND ITS DETAILED INTERACTION WITH SUBTILISIN [J].
BODE, W ;
PAPAMOKOS, E ;
MUSIL, D ;
SEEMUELLER, U ;
FRITZ, H .
EMBO JOURNAL, 1986, 5 (04) :813-818
[3]   KINETIC-STUDIES ON THE INTERACTION OF EGLIN-C WITH HUMAN-LEUKOCYTE ELASTASE AND CATHEPSIN-G [J].
BRAUN, NJ ;
BODMER, JL ;
VIRCA, GD ;
METZVIRCA, G ;
MASCHLER, R ;
BIETH, JG ;
SCHNEBLI, HP .
BIOLOGICAL CHEMISTRY HOPPE-SEYLER, 1987, 368 (04) :299-308
[4]  
CANTIN A, 1985, EUR J RESPIR DIS, V66, P7
[5]   INACTIVATION OF BRONCHIAL MUCOUS PROTEINASE-INHIBITOR BY CIGARETTE-SMOKE AND PHAGOCYTE-DERIVED OXIDANTS [J].
CARP, H ;
JANOFF, A .
EXPERIMENTAL LUNG RESEARCH, 1980, 1 (03) :225-237
[6]   POTENTIAL MEDIATOR OF INFLAMMATION - PHAGOCYTE-DERIVED OXIDANTS SUPPRESS THE ELASTASE-INHIBITORY CAPACITY OF ALPHA1-PROTEINASE INHIBITOR INVITRO [J].
CARP, H ;
JANOFF, A .
JOURNAL OF CLINICAL INVESTIGATION, 1980, 66 (05) :987-995
[7]  
CLARK RA, 1981, J BIOL CHEM, V256, P3348
[9]   OXYGEN-TOXICITY, OXYGEN RADICALS, TRANSITION-METALS AND DISEASE [J].
HALLIWELL, B ;
GUTTERIDGE, JMC .
BIOCHEMICAL JOURNAL, 1984, 219 (01) :1-14
[10]   THE INHIBITION BY DIPHENYLENEIODONIUM AND ITS ANALOGS OF SUPEROXIDE GENERATION BY MACROPHAGES [J].
HANCOCK, JT ;
JONES, OTG .
BIOCHEMICAL JOURNAL, 1987, 242 (01) :103-107