AMPUTATION LEVEL-DEPENDENT PATTERNING IN URODELE LIMB REGENERATION

被引:3
|
作者
DINSMORE, CE [1 ]
HANKEN, J [1 ]
机构
[1] UNIV COLORADO,DEPT ENVIRONM POPULAT & ORGANISM BIOL,BOULDER,CO 80309
关键词
D O I
10.1002/jmor.1052050108
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
Comparison of mesopodial skeletal patterns found in native and regenerated limbs of the salamander Plethodon cinereus reveals variant patterns unique to each group. Variant patterns in native limbs are based on fusions between laterally adjacent elements (i.e., in the anteroposterior axis). Variant patterns in the mesopodia of regenerated limbs usually exhibit fusions among proximodistally adjacent elements. Analysis of regenerates derived from limb amputation at different levels shows that the axis of fusion between regenerated mesopodial elements remains the same (i.e., proximodistal) independent of amputation level. However, the frequency of specific fusion combinations is unexpectedly sensitive to amputation level. Proximal (stylopodial) amputation results in mesopodial patterns with predominantly preaxial fusion combinations; distal amputation produces mesopodial patterns with predominantly postaxial fusion combinations. This finding is discussed in the context of other recent studies in which amputation level influenced limb regeneration patterning. Copyright © 1990 Wiley‐Liss, Inc.
引用
收藏
页码:77 / 84
页数:8
相关论文
共 50 条
  • [21] Identification of early response genes during urodele limb regeneration
    Kittappa, R
    Simon, HG
    DEVELOPMENTAL BIOLOGY, 1998, 198 (01) : 175 - 175
  • [23] TEST OF A MODEL FOR THE EFFECTS OF RETINOIC ACID ON URODELE LIMB REGENERATION
    LUDOLPH, DC
    CAMERON, JA
    STOCUM, DL
    DEVELOPMENTAL DYNAMICS, 1993, 198 (02) : 77 - 85
  • [24] The expression pattern of tomoregulin-1 in urodele limb regeneration and mouse limb development
    da Silva, SM
    Gates, PB
    Eib, DW
    Martens, GJM
    Brockes, JP
    MECHANISMS OF DEVELOPMENT, 2001, 104 (1-2) : 125 - 128
  • [25] Regenerative Engineering of a Limb: From Amputation to Regeneration
    Abedini, Amir Abbas
    Hosseini, Fatemeh
    Laurencin, Cato T.
    REGENERATIVE ENGINEERING AND TRANSLATIONAL MEDICINE, 2024, 10 (04) : 461 - 479
  • [26] Selection of level for lower limb amputation
    Hunter, GA
    CURRENT ORTHOPAEDICS, 1996, 10 (04): : 239 - 246
  • [27] On the level-dependent attenuation of a perforated device
    Chen, Lan
    Sang, Jinqiu
    Li, Xiaodong
    JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 2009, 125 (05): : 2995 - 3005
  • [28] EFFECT OF NERVE ON MORPHOLOGICAL INTEGRITY AND REGENERATION OF TRANSPLANTED LARVAL URODELE LIMB
    TAZIMA, I
    INOUE, S
    ANNOTATIONES ZOOLOGICAE JAPONENSES, 1977, 50 (04) : 231 - 244
  • [29] Can insights into urodele limb regeneration be achieved with cell cultures and retroviruses?
    Tsonis, PA
    DelRioTsonis, K
    Wallace, JL
    Burns, JC
    Hofmann, MC
    Millan, JL
    Washabaugh, CH
    INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 1996, 40 (04): : 813 - 816
  • [30] Level-Dependent Subcortical to Continuous Speech
    Kulasingham, Joshua P.
    Innes-Brown, Hamish
    Enqvist, Martin
    Alickovic, Emina
    ENEURO, 2024, 11 (08) : 16 - 16