RHABDOMYOSARCOMA - A CYTOGENETICALLY INTERESTING CASE-REPORT

被引：10
作者：
GLADSTONE, B
PARIKH, PM
BALSARA, B
KADAM, PR
RAO, SR
NAIR, CN
JAMBEKAR, NA
ADVANI, SH
机构：
[1] TATA MEM HOSP,DEPT MED ONCOL,BOMBAY 400012,INDIA
[2] TATA MEM HOSP,DEPT PATHOL,BOMBAY 400012,INDIA
来源：
CANCER GENETICS AND CYTOGENETICS | 1993年 / 66卷 / 01期
关键词：
D O I：
10.1016/0165-4608(93)90147-E
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Chromosomal analysis was performed on the tumor tissue in a case of ocular rhabdomyosarcoma. Cytogenetic analysis revealed multiple clonal abnormalities. Derivative(5)t(1;5)(q21;q35) and t(2;11) (q21;q23) were present in all the metaphases analyzed (100%). Translocation(1;19)(q21;q13) was observed in 61% of the metaphases. Other clonal abnormalities present included + i(6p) (85%), i(17q) (38%), 18q + (57%), 4p + (38%), loss of the Y chromosome (33%), and presence of double minutes (12.8%).
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页码：43 / 46
页数：4
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