CARDIORESPIRATORY EFFECTS OF COMBINED MIDAZOLAM AND BUTORPHANOL IN ISOFLURANE-ANESTHETIZED CATS

被引：15
作者：
GROSS, ME [1 ]
SMITH, JA [1 ]
TRANQUILLI, WJ [1 ]
机构：
[1] UNIV ILLINOIS,COLL VET MED,DEPT VET CLIN MED,URBANA,IL 61801
来源：
VETERINARY SURGERY | 1993年 / 22卷 / 02期
关键词：
D O I：
10.1111/j.1532-950X.1993.tb01692.x
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The cardiorespiratory effects of midazolam (0.1 mg/kg) and butorphanol (0.4 mg/kg) were evaluated in seven cats. Cats were induced in a chamber, removed and intubated, and maintained with isoflurane in 100% oxygen. Cardiorespiratory data were recorded before and 3, 10, 20, 30, 40, 50, and 60 minutes after intravenous injection of midazolam-butorphanol. Heart rate, mean arterial pressure, and respiration rate were significantly (p < .05) decreased below baseline at various times throughout the study. Tidal volume and minute ventilation were unchanged. End-tidal carbon dioxide was significantly (p < .05) increased above baseline for 30 minutes. Midazolam-butorphanol administered intravenously induced significant alterations in several cardiorespiratory parameters in isoflurane-anesthetized cats.
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页码：159 / 162
页数：4
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