STAIN ANALYSIS USING OLIGONUCLEOTIDE PROBES SPECIFIC FOR SIMPLE REPETITIVE DNA-SEQUENCES

被引：28

作者：

ROEWER, L ^{[1
]}

NURNBERG, P ^{[1
]}

FUHRMANN, E ^{[1
]}

ROSE, M ^{[1
]}

PROKOP, O ^{[1
]}

EPPLEN, JT ^{[1
]}

机构：

[1] MAX PLANCK INST PSYCHIAT,W-8033 MARTINSRIED,GERMANY

来源：

FORENSIC SCIENCE INTERNATIONAL | 1990年 / 47卷 / 01期

关键词：

DNA degradation; DNA fingerprinting; Oligonucleotide probes; Simple repetitive DNA; Stain analysis;

D O I：

10.1016/0379-0738(90)90285-7

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

The use of oligonucleotide fingerprinting is evaluated in practical forensic work, using both artificially and systematically produced stains as well as actual case work material. The probes (CAC)5 (GTG)5 are superior because of their individualizing potential in comparatively fresh specimens with little DNA degradation, whereas (GACA)4 still produces substantial information when high molecular weight DNA is lacking. The overall limitations and the advantages of this technology are discussed in detail and compared to the classical minisatellite probes. © 1990.

引用

页码：59 / 70

页数：12

共 18 条

[1]

ALI S, 1986, HUM GENET, V74, P239

[2]

BAR W, 1988, ADV FORENSIC HAEMOGE, V2, P392

[3] RED CELL ENZYME POLYMORPHISMS IN FORENSIC SEROLOGY [J].