REACTION OF TRI-2-THIENYLMETHYLLITHIUM WITH ALKYL-HALIDES - SUBSTITUTION ON CARBANION CENTER VS THIOPHENE RING

被引：17

作者：

NAKAYAMA, J

SUGINO, M

ISHII, A

HOSHINO, M

机构：

来源：

CHEMISTRY LETTERS | 1992年 / 04期

关键词：

D O I：

10.1246/cl.1992.703

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Tri-2-thienylmethyllithium, produced by treatment of tri-2-thienyl-methane with butyllithium in the presence of N,N,N',N'-tetramethyl-ethylenediamine at -78-degrees-C in tetrahydrofuran, reacts with primary alkyl halides to give the alkylated products on the carbanion center nearly quantitatively, while the reaction with secondary and tertiary alkyl halides affords not only the substitution products at the carbanion center but also those at the 3-position of the thiophene ring.

引用

页码：703 / 706

页数：4

共 32 条

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