Biological agents in psoriatic arthritis

被引：0

作者：

Kocijan, Roland ^{[1
]}

Muschitz, Christian ^{[1
]}

Rech, Juergen ^{[2
,3
]}

机构：

[1] Med Univ Vienna, Acad Teaching Hosp, VINFORCE Study Grp, Stumpergasse 13, A-1060 Vienna, Austria

[2] Univ Erlangen Nurnberg, Dept Internal Med 3, D-91054 Erlangen, Germany

[3] Univ Erlangen Nurnberg, Inst Clin Immunol, D-91054 Erlangen, Germany

来源：

WIENER MEDIZINISCHE WOCHENSCHRIFT | 2015年 / 165卷 / 1-2期

关键词：

Psoriatic arthritis; Biological agents; Anti-TNFs;

D O I：

10.1007/s10354-014-0300-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Anti-tumor necrosis factors (TNFs) are effective drugs for the treatment of psoriatic arthritis (PsA) regarding reduction of pain and inflammation, enthesitis, dactylitis, as well as psoriatic skin and nail disease. Moreover, radiographic progression in PsA is decelerated. The efficacy of anti-TNFs seems to be independent of synthetic disease-modifying anti-rheumatic drugs, suggesting only a minor role of combination therapy in PsA. Anti-TNFs are generally well tolerated in patients with PsA. Adverse events are similar to those reported in patients with rheumatoid arthritis. Ustekinumab, a recently approved IL-12/IL-23-antibody is another promising biological agent in the treatment of PsA.

引用

页码：36 / 39

页数：4

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