Amniotic membrane extract and eye drops: a review of literature and clinical application

被引：83

作者：

Murri, Michael S. ^{[1
]}

Moshirfar, Majid ^{[1
,2
]}

Birdsong, Orry C. ^{[2
]}

Ronquillo, Yasmyne C. ^{[2
]}

Ding, Yanning ^{[2
]}

Hoopes, Phillip C. ^{[2
]}

机构：

[1] Univ Utah, Sch Med, Dept Ophthalmol & Visual Sci, John A Moran Eye Ctr, Salt Lake City, UT USA

[2] Hoopes Vis, HDR Res Ctr, Draper, UT USA

来源：

CLINICAL OPHTHALMOLOGY | 2018年 / 12卷

关键词：

amniotic membrane; amniotic membrane extract; amniotic membrane extract eye drops; AME; AMEED; AMT; umbilical cord; amnion; Regenesol; Genesis; Regener-Eyes; corneal wound healing; amniotic membrane transplant;

D O I：

10.2147/OPTH.S165553

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The amniotic membrane (AM) has a long history of use in the treatment of various diseases of the ocular surface. It contains pluripotent cells, highly organized collagen, anti-fibrotic and anti-inflammatory cytokines, immune-modulators, growth factors, and matrix proteins. It is used to promote corneal healing in severely damaged eyes. Recently, AM extract and AM extract eye drops have been successfully used in clinical applications, including dry eye and chemical burns. We provide an overview on the recent progress in the preparation, mechanisms of action, and use of AM extract/AM extract eye drops for corneal and external eye diseases.

引用

页码：1105 / 1112

页数：8

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