COPY-CHOICE ILLEGITIMATE DNA RECOMBINATION REVISITED

被引：41

作者：

DALENCON, E ^{[1
]}

PETRANOVIC, M ^{[1
]}

MICHEL, B ^{[1
]}

NOIROT, P ^{[1
]}

AUCOUTURIER, A ^{[1
]}

UZEST, M ^{[1
]}

EHRLICH, SD ^{[1
]}

机构：

[1] RUDJER BOSKOVIC INST, ZAGREB 41000, CROATIA

来源：

EMBO JOURNAL | 1994年 / 13卷 / 11期

关键词：

COPY-CHOICE DNA RECOMBINATION; ESCHERICHIA COLI;

D O I：

10.1002/j.1460-2075.1994.tb06563.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nearly precise excision of a transposon related to Tn10 from an Escherichia coli plasmid was used as a model to study illegitimate DNA recombination between short direct repeats. The excision was stimulated 100-1000 times by induction of plasmid single-stranded DNA synthesis and did not involve transfer of DNA from the parental to the progeny molecule. We conclude that it occurred by copy-choice DNA recombination, and propose that other events of recombination between short direct repeats might be a result of the same process.

引用

页码：2725 / 2734

页数：10

共 83 条

[1] ON THE FORMATION OF SPONTANEOUS DELETIONS - THE IMPORTANCE OF SHORT SEQUENCE HOMOLOGIES IN THE GENERATION OF LARGE DELETIONS [J].