SYNERGISTIC COMBINATION OF AZITHROMYCIN AND SULFADIAZINE FOR TREATMENT OF TOXOPLASMOSIS IN MICE

被引：10
作者：
ARAUJO, FG
LIN, T
REMINGTON, JS
机构：
[1] PALO ALTO MED FDN,RES INST,860 BRYANT ST,PALO ALTO,CA 94301
[2] STANFORD UNIV,MED CTR,SCH MED,DEPT MED,DIV INFECT DIS,STANFORD,CA 94305
来源：
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 1992年 / 11卷 / 01期
关键词：
D O I：
10.1007/BF01971278
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Experiments were performed in vivo in a mouse model of acute toxoplasmosis to evaluate the effectiveness of the combination azithromycin/sulfadiazine. Azithromycin alone or sulfadiazine alone, at doses that did not provide any protection against death due to toxoplasmosis, were remarkably and significantly synergistic against murine toxoplasmosis when administered in combination.
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页码：71 / 73
页数：3
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