ANDROGENIC INFLUENCES ON APOMORPHINE-INDUCED YAWNING IN RATS

被引：31

作者：

BERENDSEN, HHG ^{[1
]}

NICKOLSON, VJ ^{[1
]}

机构：

[1] ORGANON SCI DEV GRP, DEPT CNS PHARMACOL, OSS, NETHERLANDS

来源：

BEHAVIORAL AND NEURAL BIOLOGY | 1981年 / 33卷 / 01期

关键词：

D O I：

10.1016/S0163-1047(81)92306-2

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The effects of steroid sex hormones on low (0.08 mg/kg s.c.) apomorphine induced yawning in rats were studied. Yawning was less in female than in male rats. Castration of male, but not of female rats reduced yawning considerably. Three days treatment with testosterone propionate (50 or 100 .mu.g/rat daily) or dihydrotestosterone (same doses) increased yawning, both in castrated male and in intact and ovariectomized female rats. Androgenic effects of testosterone propionate were larger than those of dihydrotestosterone, whereas effects on yawning were similar. Apparently apomorphine induced yawning is under androgenic influence and that estrogens play no or a minor role.

引用

页码：123 / 128

页数：6

共 11 条

[1]

EUVRARD C, 1980, J PHARMACOL EXP THER, V214, P179

[2] BRAIN-STEM CATECHOLAMINE NEURONS ARE TARGET SITES FOR SEX STEROID-HORMONES [J].

HERITAGE, AS ;

STUMPF, WE ;

SAR, M ;

GRANT, LD .

SCIENCE, 1980, 207 (4437) :1377-1379

[3] ESTROGEN-TREATMENT ENHANCES DOPAMINE RECEPTOR SENSITIVITY IN THE RAT STRIATUM [J].

HRUSKA, RE ;

SILBERGELD, EK .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1980, 61 (04) :397-400

[4] INVIVO PATTERNS OF CIRCULATING STEROIDS IN ADULT MALE RATS .1. VARIATIONS IN TESTOSTERONE DURING 24-HOUR AND 48-HOUR STANDARD AND REVERSE LIGHT-DARK CYCLES [J].

KEATING, RJ ;

TCHOLAKIAN, RK .

ENDOCRINOLOGY, 1979, 104 (01) :184-188

[5] NEURAL STEROID-HORMONE RECEPTORS [J].

MCEWEN, BS ;

GERLACH, JL ;

LUINE, VN ;

LIEBERBURG, I .

PSYCHONEUROENDOCRINOLOGY, 1977, 2 (03) :249-255

[6]

Naftolin F, 1975, Recent Prog Horm Res, V31, P295

[7] EFFECTS OF THE POTENTIAL NEUROLEPTIC PEPTIDE DES-TYROSINE1-GAMMA-ENDORPHIN AND HALOPERIDOL ON APOMORPHINE-INDUCED BEHAVIORAL SYNDROMES IN RATS AND MICE [J].

NICKOLSON, VJ ;

BERENDSEN, HHG .

LIFE SCIENCES, 1980, 27 (15) :1377-1385

[8] DETAILED ANALYSIS OF THE EFFECTS OF APOMORPHINE AND D-AMPHETAMINE ON SPONTANEOUS LOCOMOTOR BEHAVIOR OF RATS AS MEASURED IN A TV-BASED, AUTOMATED OPEN-FIELD SYSTEM [J].

NICKOLSON, VJ .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1981, 72 (01) :45-56

[9] TESTOSTERONE POTENTIATION OF THE EFFECTIVENESS OF ACTH1-24 ON THE INDUCTION OF THE STRETCH-YAWNING SYNDROME (SYS) IN MALE GUINEA-PIGS [J].

RODRIGUEZSIERRA, JF ;

TERASAWA, E ;

GOLDFOOT, DA ;

DEWIED, D .

HORMONES AND BEHAVIOR, 1981, 15 (01) :77-85

[10]

SAUNDERS FJ, 1957, P SOC EXP BIOL MED, V94, P646

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