THE DYNAMIC CLAMP - ARTIFICIAL CONDUCTANCES IN BIOLOGICAL NEURONS

被引：215

作者：

SHARP, AA ^{[1
]}

ONEIL, MB ^{[1
]}

ABBOTT, LF ^{[1
]}

MARDER, E ^{[1
]}

机构：

[1] BRANDEIS UNIV,CTR COMPLEX SYST,WALTHAM,MA 02254

来源：

TRENDS IN NEUROSCIENCES | 1993年 / 16卷 / 10期

关键词：

D O I：

10.1016/0166-2236(93)90004-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The dynamic clamp is a novel method that uses computer simulation to introduce conductances into biological neurons. This method can be used to study the role of various conductances in shaping the activity of single neurons, or neurons within networks. The dynamic clamp can also be used to form circuits from previously unconnected neurons. This approach makes computer simulation in interactive experimental tool, and will be useful in many applications where the role of synaptic strengths and intrinsic properties in neuronal and network dynamics is of interest

引用

页码：389 / 394

页数：6

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