HETEROLEPTIC TRIPODAL COMPLEXES OF COPPER(II) - TOWARDS A SYNTHETIC MODEL FOR THE ACTIVE-SITE IN GALACTOSE-OXIDASE

被引：44

作者：

ADAMS, H ^{[1
]}

BAILEY, NA ^{[1
]}

DEBARBARIN, COR ^{[1
]}

FENTON, DE ^{[1
]}

HE, OY ^{[1
]}

机构：

[1] UNIV SHEFFIELD,DEPT CIVIL & STRUCT ENGN,SHEFFIELD S3 7HF,S YORKSHIRE,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS | 1995年 / 14期

关键词：

D O I：

10.1039/dt9950002323

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of copper(II) complexes derived from tripodal ligands (HL) bearing pyridyl and phenolic arms have been synthesized and characterized. The molecular structures of complexes [CuL(4)(O(2)CMe)]. H2O and [CuL(4)(SCN)]. MeCO(2)Et {HL(4) = 2-bis[2-(2-pyridyl)ethyl]aminomethyl-4-nitrophenol} were determined by X-ray diffraction; the complexes exist as neutral, mononuclear species in the solid state. The co-ordination geometry around the copper atom in each is a distorted square-based pyramid (tau = 0.08 and 0.11) where one pyridyl nitrogen occupies the axial position (Cu-N-py 2.27 and 2.20 Angstrom). Three ligand donor atoms comprising the square plane are unchanged but the fourth ligand is an exogenous donor atom from MeCO(2)(-) or SCN- respectively. Reference is made to the relationship of the structures to that found at the copper(II) centre at the active site of galactose oxidase.

引用

页码：2323 / 2331

页数：9

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