Expert Consensus on The Management of Dermatophytosis in India (ECTODERM India)

被引:115
作者
Rajagopalan, Murlidhar [1 ,12 ]
Inamadar, Arun [2 ]
Mittal, Asit [3 ]
Miskeen, Autar K. [4 ]
Srinivas, C. R. [5 ]
Sardana, Kabir [6 ]
Godse, Kiran [7 ]
Patel, Krina [8 ]
Rengasamy, Madhu [9 ]
Rudramurthy, Shivaprakash [10 ]
Dogra, Sunil [11 ]
机构
[1] Apollo Hosp, Dept Dermatol, Madras, Tamil Nadu, India
[2] BLDE Deemed Univ, SBMP Med Coll, Dept Dermatol, Bijapur, India
[3] RNT Med Coll & Hosp, Dept Dermatol, Udaipur, India
[4] Dr Miskeens Cent Clin Microbiol Lab, Thana, India
[5] PSG Hosp, Dept Dermatol, Coimbatore, Tamil Nadu, India
[6] Dr Ram Manohar Lohia Hosp & Post Grad Inst Med Ed, Dept Dermatol Venereol & Leprosy, New Delhi, India
[7] Padmashree Dr DY Patil Univ, Dept Dermatol, Navi Mumbai, India
[8] GMERS Med Coll & Hosp, Dept Dermatol, Ahmadabad, Gujarat, India
[9] Madras Med Coll & Govt Gen Hosp, Dept Dermatol Mycol, Madras, Tamil Nadu, India
[10] Postgrad Inst Med Educ & Res PGIMER, Dept Med Microbiol, Mycol Div, Chandigarh, India
[11] Postgrad Inst Med Educ & Res PGIMER, Dept Dermatol, Chandigarh, India
[12] Apollo Hosp, Dept Dermatol, Greams Rd 21,Greams Lane,Off Greams Rd, Madras, Tamil Nadu, India
关键词
Dermatophytosis; Consensus; Tinea; Delphi; naive; Recalcitrant; Combination therapy;
D O I
10.1186/s12895-018-0073-1
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Dermatophytosis management has become an important public health issue, with a large void in research in the area of disease pathophysiology and management. Current treatment recommendations appear to lose their relevance in the current clinical scenario. The objective of the current consensus was to provide an experience-driven approach regarding the diagnosis and management of tinea corporis, cruris and pedis. Methods: Eleven experts in the field of clinical dermatology and mycology participated in the modified Delphi process consisting of two workshops and five rounds of questionnaires, elaborating definitions, diagnosis and management. Panel members were asked to mark "agree" or "disagree" beside each statement, and provide comments. More than 75% of concordance in response was set to reach the consensus. Result: KOH mount microscopy was recommended as a point of care testing. Fungal culture was recommended in chronic, recurrent, relapse, recalcitrant and multisite tinea cases. Topical monotherapy was recommended for naive tinea cruris and corporis (localised) cases, while a combination of systemic and topical antifungals was recommended for naive and recalcitrant tinea pedis, extensive lesions of corporis and recalcitrant cases of cruris and corporis. Because of the anti-inflammatory, antibacterial and broad spectrum activity, topical azoles should be preferred. Terbinafine and itraconazole should be the preferred systemic drugs. Minimum duration of treatment should be 2-4 weeks in naive cases and > 4 weeks in recalcitrant cases. Topical corticosteroid use in the clinical practice of tinea management was strongly discouraged. Conclusion: This consensus guideline will help to standardise care, provide guidance on the management, and assist in clinical decision-making for healthcare professionals.
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页数:11
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