ACTIVITY OF THYMIDYLATE SYNTHETASE AND ITS INHIBITION BY 5-FLUOROURACIL IN HIGHLY ENZYME-OVERPRODUCING CELLS RESISTANT TO 10-PROPARGYL-5,8-DIDEAZAFOLATE

被引：0

作者：

DANENBERG, KD

DANENBERG, PV

机构：

[1] UNIV SO CALIF, SCH MED, COMPREHENS CANC CTR, 1303 N MISSION RD, LOS ANGELES, CA 90033 USA

[2] UNIV SO CALIF, SCH MED, DEPT BIOCHEM, LOS ANGELES, CA 90033 USA

来源：

MOLECULAR PHARMACOLOGY | 1989年 / 36卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：219 / 223

页数：5

共 9 条

[1] SELECTION AND PROPERTIES OF LEISHMANIA-TROPICA RESISTANT TO 10-PROPARGYL-5,8-DIDEAZAFOLATE, AN INHIBITOR OF THYMIDYLATE SYNTHETASE
GARVEY, EP
CODERRE, JA
SANTI, DV
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1985, 17 (01) : 79 - 91
[2] THE ENHANCEMENT OF THE ACTIVITY OF 10-PROPARGYL-5,8-DIDEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE BY INHIBITORS OF DIHYDROFOLATE-REDUCTASE
GALIVAN, J
RHEE, MS
JOHNSON, TB
CHOU, TC
NAIR, MG
BUNNI, M
PRIEST, D
ADVANCES IN ENZYME REGULATION, VOL 28, 1989, 28 : 13 - 21
[3] THE ENHANCEMENT OF THE ACTIVITY OF 10-PROPARGYL-5,8-DIDEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE BY INHIBITORS OF DIHYDROFOLATE-REDUCTASE
GALIVAN, J
RHEE, MS
JOHNSON, TB
CHOU, TC
NAIR, MG
BUNNI, M
PRIEST, D
ADVANCES IN ENZYME REGULATION, 1989, 28 : 13 - 21
[4] CRYSTAL-STRUCTURE OF ESCHERICHIA-COLI THYMIDYLATE SYNTHASE CONTAINING BOUND 5-FLUORO-2'-DEOXYURIDYLATE AND 10-PROPARGYL-5,8-DIDEAZAFOLATE
MATTHEWS, DA
APPELT, K
OATLEY, SJ
XUONG, NH
JOURNAL OF MOLECULAR BIOLOGY, 1990, 214 (04) : 923 - 936
[5] THE ROLE OF CELLULAR FOLATES IN THE ENHANCEMENT OF ACTIVITY OF THE THYMIDYLATE SYNTHASE INHIBITOR 10-PROPARGYL-5,8-DIDEAZAFOLATE AGAINST HEPATOMA-CELLS INVITRO BY INHIBITORS OF DIHYDROFOLATE-REDUCTASE
GALIVAN, J
RHEE, MS
JOHNSON, TB
DILWITH, R
NAIR, MG
BUNNI, M
PRIEST, DG
JOURNAL OF BIOLOGICAL CHEMISTRY, 1989, 264 (18) : 10685 - 10692
[6] ACTIVITY OF THE NEW ANTIFOLATE N-10-PROPARGYL-5,8-DIDEAZAFOLATE AND ITS POLYGLUTAMATES AGAINST HUMAN DIHYDROFOLATE-REDUCTASE, HUMAN THYMIDYLATE SYNTHETASE, AND KB CELLS CONTAINING DIFFERENT LEVELS OF DIHYDROFOLATE-REDUCTASE
CHENG, YC
DUTSCHMAN, GE
STARNES, MC
FISHER, MH
NANAVATHI, NT
NAIR, MG
CANCER RESEARCH, 1985, 45 (02) : 598 - 600
[7] THE EFFICACY OF 5-FLUOROURACIL IN HUMAN COLORECTAL-CANCER IS NOT ENHANCED BY THYMIDYLATE SYNTHETASE INHIBITION WITH CB3717 (N-10-PROPARGYL-5,8 DIDEAZAFOLIC ACID)
CANTWELL, BMJ
HARRIS, AL
BRITISH JOURNAL OF CANCER, 1988, 58 (02) : 189 - 190
[8] THE EFFECTS OF 5-FLUOROURACIL (FU) ON MOUSE FM3A CELLS WITH HIGHLY AMPLIFIED THYMIDYLATE SYNTHETASE (TS) ACTIVITY
DANENBERG, K
DANENBERG, PV
PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1987, 28 : 322 - 322
[9] ACTIVITY OF THE NEW ANTIFOLATE, N-10 PROPARGYL-5, 8-DIDEAZA FOLATE(PDDF), AND ITS POLYGLUTAMATES AGAINST HUMAN DIHYDROFOLATE-REDUCTASE (DHFR), HUMAN THYMIDYLATE SYNTHETASE(TMPS) AND KB CELLS CONTAINING DIFFERENT LEVELS OF DHFR
DUTSCHMAN, GE
STARNES, MC
FISHER, MH
NAVAPHI, NT
NAIR, MG
CHENG, YC
FEDERATION PROCEEDINGS, 1984, 43 (04) : 950 - 950

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