BORANE COMPLEXES OF VINBLASTINE TYPE DIINDOLE DERIVATIVES

被引：6

作者：

BALAZS, M

SZANTAY, C

BOLCSKEI, H

SZANTAY, C

机构：

[1] HUNGARIAN ACAD SCI,CENT RES INST CHEM,POB 17,H-1025 BUDAPEST,HUNGARY

[2] GEDEON RICHTER CHEM WORKS LTD,CHEM WORKS,H-1475 BUDAPEST,HUNGARY

[3] GEDEON RICHTER CHEM WORKS LTD,SPECTROSCOP RES CTR,H-1475 BUDAPEST,HUNGARY

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 27期

关键词：

ANHYDROVINBLASTINE; 20'-DEETHYL-AVLB; N-DEMETHYL-AVLB; BORANE COMPLEXES; FECL3; COUPLING;

D O I：

10.1016/S0040-4039(00)79362-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

While investigating the ferric chloride mediated coupling1 of catharanthine (1) with vindoline (3) and their derivatives (2,4), the borane complexes of 15',20'-anhydrovinblastine2 (AVLB), 20'-deethyl-AVLB and N-demethyl-AVLB (9,10,11) have been synthesized. The corresponding bases (6,7 and 8) have also been obtained in high yield.

引用

页码：4397 / 4398

页数：2

共 9 条

[1] 20'-DEETHYLANHYDROVINBLASTINE [J].