Deep Vein Thrombosis in a Patient With Lepromatous Leprosy Receiving Thalidomide to Treat Leprosy Reaction

被引：8

作者：

Petiti-Martin, G. Hebe ^{[1
]}

Villar-Buill, M. ^{[1
]}

de la Hera, I. ^{[1
]}

Fuertes, L. ^{[1
]}

Burgues-Calderon, M. ^{[1
]}

Rivera-Diaz, R. ^{[1
]}

Vanaclocha, F. ^{[1
]}

机构：

[1] Hosp 12 Octubre, Serv Dermatol, Madrid, Spain

来源：

ACTAS DERMO-SIFILIOGRAFICAS | 2013年 / 104卷 / 01期

关键词：

Hansen disease; Leprosy; Leprosy reaction; Thalidomide; Deep vein thrombosis;

D O I：

10.1016/j.ad.2011.12.002

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Thalidomide is the treatment of choice for severe or recurrent erythema nodosum leprosum. Its use has been associated with deep vein thrombosis in patients with blood disorders, however, particularly when used in combination with corticosteroids or chemotherapy. We describe a case of deep vein thrombosis in a 43-year-old man with lepromatous leprosy who was being treated with thalidomide and prednisone for a type 2 leprosy reaction (erythema nodosum leprosum); the patient also had transiently positive antiphospholipid antibody results. We stress the importance of considering deep vein thrombosis, a potentially fatal complication, in dermatology patients treated with thalidomide. (C) 2011 Elsevier Espana, S.L. and AEDV. All rights reserved.

引用

页码：67 / 70

页数：4

共 19 条

[1] Leprosy & gangrene:: A rare association;: role of anti phospholipid antibodies -: art. no. 74 [J].