WORSENING TO DIABETES IN MEN WITH IMPAIRED GLUCOSE-TOLERANCE (BORDERLINE DIABETES)

被引:197
作者
JARRETT, RJ [1 ]
KEEN, H [1 ]
FULLER, JH [1 ]
MCCARTNEY, M [1 ]
机构
[1] GUYS HOSP,SCH MED,METAB MED UNIT,LONDON SE1 9RT,ENGLAND
关键词
borderline diabetes; diabetes mellitus; impaired glucose tolerance;
D O I
10.1007/BF00423146
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Two hundred and four men with impaired glucose tolerance (borderline diabetes) discovered in a screening examination have been observed for five years and repeated tests of glucose tolerance performed. By pre-determined criteria 27 men 'worsened to diabetes' and this metabolic deterioration was not significantly influenced by treatment with carbohydrate restriction with or without a daily dose of 50 mg phenformin. Of the baseline variables measured prior to treatment allocation only the blood glucose values were significantly predictive of ultimate worsening to diabetes. © 1979 Springer-Verlag.
引用
收藏
页码:25 / 30
页数:6
相关论文
共 14 条
[1]   THE ELECTROCARDIOGRAM IN POPULATION STUDIES - A CLASSIFICATION SYSTEM [J].
BLACKBURN, H ;
KEYS, A ;
SIMONSON, E ;
RAUTAHARJU, P ;
PUNSAR, S .
CIRCULATION, 1960, 21 (06) :1160-1175
[2]  
CARLSTROM S, 1971, ACTA MED SCAND, V189, P415
[3]   FLUOROMETRIC ASSAY OF TRIGLYCERIDE BY A SEMIAUTOMATED METHOD [J].
CRAMP, DG ;
ROBERTSON, G .
ANALYTICAL BIOCHEMISTRY, 1968, 25 (1-3) :246-+
[4]  
FELDMAN R, 1973, ADV METABOLIC DIS S2, V2, P557
[5]  
JARRETT RJ, 1976, LANCET, V2, P1009
[6]   TREATMENT OF BORDERLINE DIABETES - CONTROLLED TRIAL USING CARBOHYDRATE RESTRICTION AND PHENFORMIN [J].
JARRETT, RJ ;
KEEN, H ;
FULLER, JH ;
MCCARTNEY, M .
BRITISH MEDICAL JOURNAL, 1977, 2 (6091) :861-865
[7]   FOLLOW-UP OF NON-DIABETIC RELATIVES OF DIABETICS BY RETESTING ORAL GLUCOSE-TOLERANCE AFTER 5 YEARS [J].
KOBBERLING, J ;
KATTERMANN, R ;
ARNOLD, A .
DIABETOLOGIA, 1975, 11 (05) :451-456
[8]   AUTOMATED DETERMINATION OF SERUM TOTAL CHOLESTEROL [J].
LEVINE, JB ;
ZAK, B .
CLINICA CHIMICA ACTA, 1964, 10 (04) :381-&
[9]   PROSPECTIVE STUDY OF 352 YOUNG PATIENTS WITH CHEMICAL DIABETES [J].
OSULLIVAN, JB ;
MAHAN, CM .
NEW ENGLAND JOURNAL OF MEDICINE, 1968, 278 (19) :1038-+
[10]  
REID DD, 1974, LANCET, V1, P469