COLLAGEN OF HUMAN ARTICULAR AND COSTAL CARTILAGE

被引：43

作者：

MILLER, EJ

VANDERKO.JK

SOKOLOFF, L

机构：

[1] Laboratory of Biochemistry, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland

[2] Department of Internal Medicine, University of Nymegen

[3] Section on Rheumatic Diseases, Laboratory of Experimental Pathology, National Institute of Arthritis and Metabolic Diseases, Bethesda, Maryland

来源：

ARTHRITIS AND RHEUMATISM | 1969年 / 12卷 / 01期

关键词：

D O I：

10.1002/art.1780120105

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Collagen comprises approximately 90 per cent of the protein of human articular cartilage. Only about 1 per cent of the total collagen could be extracted by solutions of 5 M guanidine‐HCl from normal cartilage, and the extractability of collagen from fibrillated specimens was not elevated. In costal cartilage, the proportion of noncollagenous protein increases almost threefold during skeletal growth. Moreover, the extractability of costal cartilage collagen decreases as a function of age. Copyright © 1969 American College of Rheumatology

引用

页码：21 / &

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