LOOK-BACK STUDY OF INFECTIVITY OF ANTI-HCV ELISA-POSITIVE BLOOD COMPONENTS

被引：55
作者：
VRIELINK, H
VANDERPOEL, CL
REESINK, HW
ZAAIJER, HL
SCHOLTEN, E
KREMER, LCM
CUYPERS, HTM
LELIE, PN
VANOERS, MHJ
机构：
[1] NETHERLANDS RED CROSS,BLOOD TRANSFUS SERV,CENT LAB,AMSTERDAM,NETHERLANDS
[2] UNIV AMSTERDAM,ACAD MED CTR,1105 AZ AMSTERDAM,NETHERLANDS
来源：
LANCET | 1995年 / 345卷 / 8942期
关键词：
D O I：
10.1016/S0140-6736(95)90063-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The infectivity of blood components from donors who were later found to be anti-HCV ELISA-positive was investigated in recipients who were enrolled in a look-back programme. Recipients received ELISA-positive blood components from donors who were PCR-positive and/or RIBA-2-positive (n=22, group A) or PCR-negative and indeterminate or negative on RIBA-2 (n=105, group B). 26 of 32 (81%) recipients of group A donors and none of 140 of group B were HCV-infected. All stored serum samples of previous donations (n=172) of group A donors were anti-HCV-positive in RIBA-3, indicating a chronic carrier state of HCV in these donors.
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收藏
页码：95 / 96
页数：2
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