IN-VITRO ANTIBACTERIAL ACTIVITY OF SUCRALFATE

被引：10
作者：
BERGMANS, D
BONTEN, M
GAILLARD, C
VANTIEL, F
VANDERGEEST, S
STOBBERINGH, E
机构：
[1] UNIV LIMBURG HOSP,DEPT INTERNAL MED,6202 AZ MAASTRICHT,NETHERLANDS
[2] UNIV LIMBURG HOSP,DEPT MED MICROBIOL,6202 AZ MAASTRICHT,NETHERLANDS
来源：
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 1994年 / 13卷 / 07期
关键词：
D O I：
10.1007/BF01971318
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The effect of sucralfate (12.5 mg/ml) on the growth of Escherichia coli (ATCC 25922), Enterococcus faecalis (ATCC 29212) and two isolates of Pseudomonas aeruginosa (ATCC 27853 and a multi-resistant clinical isolate) was studied in vitro at pH values of 3.0, 4.5, 6.0 and 7.4. A bacteriostatic effect of sucralfate was demonstrated for Pseudomonas aeruginosa at a pH of 6.0 and 7.4 and for Escherichia coli and Enterococcus faecalis at a pH of 6.0. The bacteriostatic effect was most pronounced at high pH values. Sucralfate had no bactericidal effect on the bacteria tested at the concentration used.
引用
收藏
页码：615 / 620
页数：6
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