Pregabalin in Chemotherapy Induced Neuropathic Pain

被引：18

作者：

Atreya, Shrikant ^{[1
]}

机构：

[1] Tata Med Ctr, Dept Palliat Care & Psychooncol, Kolkata, W Bengal, India

来源：

INDIAN JOURNAL OF PALLIATIVE CARE | 2016年 / 22卷 / 01期

关键词：

Cancer; Chemotherapy-induced peripheral neuropathy; Pregabalin;

D O I：

10.4103/0973-1075.173941

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Chemotherapeutic agents belonging to vinca alkaloids, taxanes, and antitubulins produce peripheral neuropathy for which there is no validated treatment. Pregabalin, a gamma-aminobutyric acid analog, is known to inhibit the a2d subunit of the voltage-gated calcium channel. Earlier studies and case reports have shown pregabalin to be effective in treating neuropathic pain. We present a case series of patients with chemotherapy-induced peripheral neuropathy who were successfully treated with pregabalin with reduction in the hyperalgesia, allodynia, and improvement in the quality of life.

引用

页码：101 / 103

页数：3

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