CALCIUM IS NECESSARY IN THE CELL RESPONSE TO EM FIELDS

被引：84
作者：
KARABAKHTSIAN, R
BROUDE, N
SHALTS, N
KOCHLATYI, S
GOODMAN, R
HENDERSON, AS
机构：
[1] CUNY HUNTER COLL, DEPT BIOL SCI, NEW YORK, NY 10021 USA
[2] CUNY, GRAD DIV BIOL, NEW YORK, NY 10021 USA
[3] CUNY, GRAD DIV BIOCHEM, NEW YORK, NY 10021 USA
[4] COLUMBIA UNIV, DEPT PATHOL, NEW YORK, NY 10032 USA
来源：
FEBS LETTERS | 1994年 / 349卷 / 01期
关键词：
EXTREMELY LOW FREQUENCY (ELF) ELECTROMAGNETIC (EM) FIELDS; CALCIUM; RNA TRANSCRIPT;
D O I：
10.1016/0014-5793(94)00618-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Previous research showed that exposure of human HL-60 cells to extremely low frequency electromagnetic fields increases the steady-state levels of some mRNAs. Modifications in calcium flux have been suggested as a means of amplifying electromagnetic signals, and induced changes in calcium influx could hypothetically lead to gene activation. The present experiments tested the role of calcium in the response of cells to electromagnetic fields. Steady state transcript levels for c-fos and c-myc were determined under conditions of low extracellular calcium. The present study confirms that calcium plays a role in the response of cells to electromagnetic fields.
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页码：1 / 6
页数：6
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