NOVEL IMMUNOCHEMICAL CHARACTERISTICS OF GLUTATHIONE S-TRANSFERASE ISOZYMES OF RAT-LIVER CYTOSOL

被引：0
作者：
FUKAI, F
KURANO, M
NISHIZAWA, S
KIIRE, Y
NAGAI, T
KATAYAMA, T
机构：
来源：
BIOCHEMISTRY INTERNATIONAL | 1988年 / 17卷 / 05期
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暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Revaluation of the immunochemical relationships among the individual glutathione S-transferase (GST) isozymes (GSTs 1-1, 1-2, 2-2, 3-3, 3-4, 4-4, and GSTs with isoelectric points of 7.5 and 6.8) of rat liver cytosol was performed utilizing the immunoblot technique. As a result, we found that the respective isozymes of two isozyme classes of rat liver cytosol might possess a common epitope(s) which has been undetected by the Ouchterlony double-diffusion method. The assumption was further supported by the results of the effects of Fab'' prepared from some anti-GST antibodies on the enzymatic activity of GSTs.
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页码：945 / 951
页数：7
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