A MODIFIED MANNICH REACTION USING 1,3-DIOXOLANE

被引：0

作者：

SUMITA, K ^{[1
]}

KOUMORI, M ^{[1
]}

OHNO, S ^{[1
]}

机构：

[1] MARUKO PHARMACEUT CO LTD, RES LABS, KASUGAI, AICHI 486, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1994年 / 42卷 / 08期

关键词：

MANNICH REACTION; AMINOMETHYLATION; 1,3-DIOXOLANE; FORMALDEHYDE; PARAFORMALDEHYDE;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Mannich reaction of ketones using 1,3-dioxolane instead of formaldehyde, paraformaldehyde, or 1,3,5-trioxane afforded the corresponding Mannich bases in high yields. Under the same conditions the aminomethylation of aromatics did not proceed but the intramolecular aminomethylation, like a Pictet-Spengler type reaction, proceeded smoothly.

引用

页码：1676 / 1678

页数：3

共 50 条

[21] CATIONIC COPOLYMERIZATION OF 1,3-DIOXOLANE WITH STYRENE
OKADA, M
YAMASHITA, Y
ISHII, Y
MAKROMOLEKULARE CHEMIE, 1966, 94 (JUN): : 181 - +
[22] Maghnite-H+ as a cationic catalyst in the synthesis of poly(1,3-dioxolane) and α,ω-methacryloyloxy-poly(1,3-dioxolane)
Megherbi, Radja
Belbachir, Mohammed
Meghabar, Rachid
JOURNAL OF APPLIED POLYMER SCIENCE, 2006, 101 (01) : 78 - 82
[23] Maghnite-H+ as a cationic catalyst in the synthesis of poly(1,3-dioxolane) and α,ω-methacryloyloxy-poly(1,3-dioxolane)
Megherbi, Radja
Belbachir, Mohammed
Meghabar, Rachid
Journal of Applied Polymer Science, 2006, 101 (01): : 78 - 82
[24] HOMOLYTIC ADDITION OF 1,3-DIOXOLANE TO PYRIDINE
BORISOVA, IA
ZORIN, VV
ZLOTSKII, SS
RAKHMANKULOV, DL
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1979, (07): : 990 - 991
[25] POLYMERIZATION OF 1,3-DIOXOLANE IN PRESENCE OF WATER
BERMAN, EL
LYUDVIG, EB
PONOMARE.VA
MEDVEDEV, SS
DOKLADY AKADEMII NAUK SSSR, 1968, 183 (03): : 614 - &
[26] Calorimetric and DTA studies of 1,3-dioxolane hydrate and (1,3-dioxolane)(1-x)(tetrahydrofuran)(x) mixed hydrates
Yonekura, T
Yamamuro, O
Matsuo, T
Suga, H
THERMOCHIMICA ACTA, 1995, 266 : 65 - 77
[27] VOLTAMMETRIC DETERMINATION OF 1,3-DIOXOLANE HYDROPEROXIDES USING A GRAPHITE ELECTRODE
KURAMSHIN, EM
YUFEREVA, LA
MAISTRENKO, VN
ZLOTSKII, SS
RAKHMANKULOV, DL
JOURNAL OF ANALYTICAL CHEMISTRY OF THE USSR, 1984, 39 (02): : 283 - 285
[28] Cationic polymerization of 1,3-dioxolane using sacrificial initiator anodes
Djelali, Nacer-Eddine
Aliouche, Djamel
Pierre, Gerard
ANNALES DE CHIMIE-SCIENCE DES MATERIAUX, 2006, 31 (04): : 463 - 469
[29] REACTION OF DICHLOROCARBENE WITH 4-METHYLENE-1,3-DIOXOLANE SUBSTITUENTS
MOLCHANOV, AP
KOSTIKOV, RR
SERKINA, TG
BADOVSKAYA, LA
ZHURNAL ORGANICHESKOI KHIMII, 1992, 28 (10): : 2156 - 2158
[30] Synthesis of Novel 1,3-Dioxolane Nucleoside Analogues
蔡冬梅
林昆华
李明宗
温集武
李鸿艳
尤田耙
Chinese Journal of Chemistry, 2004, (12) : 1425 - 1431

← 1 2 3 4 5 →