BCR/ABL AND SRC BUT NOT MYC AND RAS REPLACE V-ABL IN LYMPHOID TRANSFORMATION

被引：26

作者：

ENGELMAN, A

ROSENBERG, N

机构：

[1] TUFTS UNIV, SCH MED, DEPT MOLEC BIOL & MICROBIOL, 136 HARRISON AVE, BOSTON, MA 02111 USA

[2] TUFTS UNIV, SCH MED, DEPT PATHOL, BOSTON, MA 02111 USA

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1990年 / 10卷 / 08期

关键词：

D O I：

10.1128/MCB.10.8.4365

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Lymphoid cells transformed by temperature-sensitive Abelson virus die at the nonpermissive temperature. This property was exploited to show that bcr/abl and v-src but not myc and ras can replace the transforming signal of v-abl, a result suggesting that the former but not the latter oncogenes transform lymphoid cells via a similar pathway.

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收藏

页码：4365 / 4369

页数：5

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