OVARIAN AND HYPOGASTRIC INNERVATION OF GUINEA-PIG UTERUS

被引:20
作者
ISAAC, PF
PENNEFATHER, JN
SILVA, DG
机构
[1] Department of Pharmacology, University of Melbourne, Parkville
[2] Department of Anatomy, Monash University, Clayton
关键词
-effects of α-receptor blockers; -effects of ′β-receptor blocker; Innervated uterus (guinea-pig); Uterine nerve stimulation;
D O I
10.1016/0014-2999(69)90117-4
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
A preparation of dioestrous guinea-pig isolated innervated uterus is described. The uterine tissue comprised one horn, the fundus and the cervix. The response to stimulation of either hypogastric or ovarian nerves was contraction recorded between the cervix and the ovarian end of the horn. Propranolol regularly caused an increase in the size of contractions in response to nerve stimulation, phenoxybenzamine and phentolamine caused a decrease and hexamethonium and atropine had no effect. Electronmicroscopy revealed a predominance of non-myelinated fibres in both the ovarian and hypogastric nerves. However, there was a relatively higher proportion of myelinated fibres in the hypogastric nerve. © 1969.
引用
收藏
页码:384 / +
页数:1
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