PROTEIN SYNTHESIS IN HIPPOCAMPAL PYRAMIDAL CELLS OF RATS DURING A BEHAVIORAL TEST

被引：80

作者：

HYDEN, H

LANGE, PW

机构：

[1] Institute of Neurobiology, Faculty of Medicine, University of Göteborg, Göteborg

来源：

SCIENCE | 1968年 / 159卷 / 3821期

关键词：

D O I：

10.1126/science.159.3821.1370

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Protein synthesis was studied in the pyramidal nerve cells of the CA3 region in the hippocampus of rats during a behavioral test involving transfer of handedness. A new electrophoretic technique was used for separation of 10 -7 to 10-9 gram of protein and radiometric determination of the various protein fractions. After interventricular administration of 3H-leucine, protein synthesis of two fast-moving fractions was significantly higher bilaterally in the hippocampus of the trained rats. There was also a trend to lateralization of the highest protein synthesis to the learning side.

引用

页码：1370 / &

共 25 条

[1]

Adey W R, 1967, Prog Brain Res, V27, P228

[2]

ADEY WR, 1961, FED PROC, V20, P617

[3] PUROMYCIN EFFECT ON MEMORY FIXATION IN GOLDFISH [J].