MALIGNANT TRANSFORMATION OF AN OSTEOBLASTOMA OF THE SKULL - AN EXCEPTIONAL OCCURRENCE - CASE-REPORT

被引:28
作者
FIGARELLABRANGER, D
PEREZCASTILLO, M
GARBE, L
GRISOLI, F
GAMBARELLI, D
HASSOUN, J
机构
[1] HOP LA TIMONE,FAC MED,DEPT NEUROPATHOL,F-13385 MARSEILLE 5,FRANCE
[2] HOP LA TIMONE,DEPT NEUROSURG,F-13385 MARSEILLE 5,FRANCE
关键词
SKULL; OSTEOBLASTOMA; MALIGNANT TRANSFORMATION;
D O I
10.3171/jns.1991.75.1.0138
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
What is apparently the first reported case of spontaneous malignant transformation of a benign osteoblastoma of the skull is described. The initial lesion was completely removed surgically and showed the histological features typical of a benign osteoblastoma. No radiotherapy was performed. Eleven years later the patient developed an osteosarcoma of the skull. Review of the literature showed that malignant transformation of benign osteoblastomas is extremely rare and could take place spontaneously. However, the risk of this occurring seems higher after inadequate initial treatment (curettage or partial excision). Follow-up monitoring of patients with osteoblastoma of the cranial vault is suggested.
引用
收藏
页码:138 / 142
页数:5
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